Downstream Processing: From Egg to Cell Culture-Derived Influenza Virus Particles
نویسندگان
چکیده
منابع مشابه
Downstream processing of cell culture-derived animal viruses
................................................................................................................................................. v List of Tables ........................................................................................................................................ ix List of Figures .................................................................................
متن کاملClinical efficacy of cell culture–derived and egg‐derived inactivated subunit influenza vaccines in healthy adults.
BACKGROUND More efficient methods are needed to manufacture influenza vaccines. This trial compared the efficacy of cell culture-derived influenza vaccine (CCIV) and egg-derived trivalent inactivated vaccine (TIV) with placebo against laboratory-confirmed influenza illness in healthy adults in the United States, Finland, and Poland during the 2007-2008 influenza season. METHODS A total of 11,...
متن کاملContinuous Influenza Virus Production in Cell Culture Shows a Periodic Accumulation of Defective Interfering Particles
Influenza viruses are a major public health burden during seasonal epidemics and a continuous threat due to their potential to cause pandemics. Annual vaccination provides the best protection against the contagious respiratory illness caused by influenza viruses. However, the current production capacities for influenza vaccines are insufficient to meet the increasing demands. We explored the po...
متن کاملEnvelope protein(s) derived from influenza virus.
Eckert, Edward A. (University of Michigan, Ann Arbor). Envelope protein(s) derived from influenza virus. J. Bacteriol. 91:1907-1910. 1966.-Lipids were extracted from influenza virus, strain PR8, with methanol-chloroform, and the protein residue was dissolved in 67% glacial acetic acid. Hemagglutinating activity and complement-fixing reactivity were markedly reduced or lost during lipid extracti...
متن کاملCharacterization of Nucleoprotein Extracted from Human Influenza A Virus Cultured in Two Different Cell Lines
Background and Aims: Influenza virus nucleoprotein (NP) has the capacity to be used as subunit vaccine, but little is known about the impact of different cultures on its structure. In the present study we aimed to evaluate and compare the Isoelectric focusing (IEF) property of extracted viral nucleoproteins derived from Madin Darby canine kidney (MDCK) cell line and embryonated chicken eggs (EC...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Engineering & Technology
سال: 2008
ISSN: 0930-7516,1521-4125
DOI: 10.1002/ceat.200800118